Скачать или смотреть How Does Lithium Dosing Frequency Influence Renal Function?

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Explore the nuanced relationship between lithium therapy and renal function. This video delves into recent studies assessing the impact of lithium on renal function, comparing it with other mood stabilisers, and discussing optimal dosing strategies to mitigate risks.

Key Learnings:

• Lithium's Renal Impact: Understand the extent to which lithium affects kidney function compared to other medications.
• Dosing Strategies: Learn why once-daily dosing may be preferable for renal safety.
• Monitoring Essentials: Grasp the importance of regular monitoring and maintaining therapeutic lithium levels.

Timestamps:

00:00 – Introduction to lithium's renal considerations
00:13 – Study overview: Lithium vs. other mood stabilisers
00:38 – Annual GFR changes and statistical significance
01:07 – Understanding confounding bias in renal assessments
01:19 – Advocating for once-daily lithium dosing
01:46 – Historical context: 1982 study on dosing frequency
01:52 – Modern data supporting once-daily dosing
02:06 – Case-control study on renal insufficiency
02:19 – Protective effects of once-daily dosing
02:48 – Importance of bedtime dosing and 12-hour levels
03:08 – Re-evaluating therapeutic lithium levels
03:30 – Recommended maintenance levels for lithium

#psychiatry #lithium therapy #renal function