Скачать или смотреть C. difficile toxin A+B rapid test — detection of C. difficile and toxins A/B

INFECTIONS FOR C. DIFFICILE

C.difficile is considered to be responsible for approximately 25% of the diarrhoea associated with the consumption of antibiotics2, including clindamycin, second- and third-generation of cephalosporins, gyrase inhibitors, ampicillin, amoxicillin and so forth.

In addition to the diarrhoea symptoms, the disease can led to pseudomembranous colitis (PMC), which requires urgent treatment with antibiotics effective against C.difficile (metronidazole, vancomycin) as the patient's life may be compromised.

The mortality associated to C.difficile can be between 6% and 30%, especially if the patient suffers from PMC.

SCREENING PROCEDURES

Some of the leading healthcare societies propose the use of a two-step protocol for identifying toxigenic C.difficile involving an initial screening of the sample with a GDH test and, if the result is positive, use of a second test to detect toxins from C.difficile as not all strains of this microorganism produce them.

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