Скачать или смотреть [Conférence] H. CLEVERS - Lgr5 stem cells and Organoids

Conférence : Exposés scientifiques de Max Cooper, Hans Clevers et Sandra Diaz, associés étrangers élus en 2015
Lien de la conférence : http://www.academie-sciences.fr/fr/Co...

00:00:00 Introduction
00:00:48 Worn-out cells are replaced by young cells. Stem cells do so by cell division
00:01:40 Every organ has its own stem cells
00:03:01 The gut harbors the champion of all stem cells
00:04:16 Joannis Nathanael Lieberkühn, thesis 1745.
00:05:47 The champion of all stem cells at work
00:06:35 Finding the gut stem cells
00:07:08 “Our” molecular flag: Lgr5
00:08:42 Charles Philippe Leblond [1910 – 2007]
00:09:29 Is the Crypt Base Columnar Cell the elusive stem cell?
00:10:03 Nick Barker creates a Knock-Out mouse [1]
00:11:33 Eureka!!
00:12:15 When we turn a stem cell blue, it reveals its daughters
00:13:48 The Confetti-mouse
00:14:22 Fifteen multi-colored stem cells in every crypt
00:16:57 Can we culture the stem cells in a dish?
00:17:40 Harvesting pure stem cells with a Cell Sorter machine
00:18:23 Growing a mini-gut from a single stem cell [Toshiro Sato]
00:20:02 Mini-guts can be transplanted
00:25:02 Personalized medicine for cancer
00:27:12 Questions


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