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Stop guessing and start reading the pattern! 🧬🤰

Most people look at antenatal labs as "just a number" or a pass/fail screening. But in clinical biochemistry, these markers are telling a much deeper story about placental health, chromosomal risk, and future complications before symptoms even appear.

Swipe through for a masterclass in interpreting pregnancy biochemistry! ➡️

🧪 What your labs are REALLY telling you:
1️⃣ hCG (Human Chorionic Gonadotropin): It’s the ultimate placental health check. Don't just look at a single value—look at the trend. A slow rise can be an early warning for ectopic or failing pregnancies.
2️⃣ Free β-hCG + PAPP-A: When combined with Nuchal Translucency (NT), these are powerhouses for aneuploidy risk. Low PAPP-A isn't just about chromosomes; it’s a major red flag for future placental insufficiency.
3️⃣ The Quad Screen: AFP, hCG, Estriol, and Inhibin A. High AFP? Think structural (NTDs). Low AFP + High hCG? Think Down syndrome risk. Pro-tip: Always double-check Gestational Age (GA) before interpreting!
4️⃣ sFlt-1 / PlGF Ratio: The "Placental Stress Test." This ratio is a game-changer for ruling out Pre-Eclampsia in the short term.
5️⃣ Early GDM Detection: Gestational Diabetes starts way before the OGTT. Watch those early fasting glucose and HbA1c levels for a head start on management.

The Golden Rule: Labs support decisions—they don’t replace them. Clinical context is everything. 🩺✨

Which of these markers do you find most challenging to interpret in clinic? Let’s discuss in the comments! 👇