Mosaicism in Turner Syndrome

TS expert geneticist, Dr. Angela Lin describes the genetics behind mosaic TS and reviews the questions below.

What is a typical male, female, and TS karyotype?
How does TS happen? It's not inherited but happens at conception and is not related to maternal age.
Dr. Lin says, "TS occurs because of the loss of the second sex chromosome
There are many chromosome variations.
Do TS features vary with chromosome type? Sometimes, it's complicated.
If 45,X is the pure form of TS, then is mosaicism a milder form of TS?
Mosaicism can vary in different tissues (blood, skin, organs) and can change with age, sometimes cell lines can be lost with age.
Learn how mosaicism affects pregnancy, how TS is diagnosed, why it's important to know your karyotype, why the term Disorders of Sexual Differences is helpful to know.








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