Скачать или смотреть Cracking the Code: Genetics in Modern Oncology

What happens when we stop gatekeeping genetic testing and offer it universally?

In this episode of Doc to Doc, Dr. Arelis Martir Negron, medical geneticist at Miami Cancer Institute, joins Dr. Venkatappa to explore how the field of cancer genetics is transforming — and what every clinician should know. From BRCA1 and BRCA2 to multi-gene panels and AI-powered risk stratification, testing this conversation covers the past, present, and bold future of universal germline testing.

Host:

Siddhartha Anantha Venkatappa, M.D.
Oncologist/Hematologist
Baptist Health Miami Cancer Institute

Guest:
Arelis Martir Negron, M.D., FAMG
Medical Geneticist
Baptist Health Miami Cancer Institute

0:00 BRCA and the Origins of Cancer Genetics
2:01 Defining Clinical Genetics and Risk
2:57 Germline vs. Somatic Mutations
4:26 Genes and Syndromes Beyond BRCA
5:43 Universal Germline Testing at MCI
8:28 Benefits and Risks of Broad Testing
10:34 Genetics and Personalized Treatment
12:53 The Primary Care Role in Genetic Referrals
14:22 Going Beyond Traditional Testing Guidelines
17:03 Referrals to MCI’s Genetic Team
21:01 Genetics Across Ethnic Populations
23:29 How AI Is Improving Genetic Interpretation
24:56 Impact of Genetics on Cancer Treatment
26:51 The Future of Precision Oncology