Discovery of RNA Targeting Small Molecule Using DNA-Encoded Library Technology

Описание к видео Discovery of RNA Targeting Small Molecule Using DNA-Encoded Library Technology

Presented by Dr. Jason Deng, Senior Director of WuXi AppTec, at Drug Discovery Chemistry 2022

Abstract: Discovery of new chemical entities modulating RNA function has been an emerging area in the past few years. Although successful against protein targets, there are a few challenges of applying DNA-encoded library (DEL) technology to discover RNA targeting molecules. Here we’d like to share the most recent successes in developing DEL screening methodology against RNA targets.

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