Скачать или смотреть Lecture On Direct & Indirect Bilirubin Estimation: Understanding Jaundice & Liver Function | MBBS

Dr. [Channel Name, if available, otherwise leave blank] explains the estimation of direct and indirect bilirubin, building upon a previous lecture about total bilirubin. This video covers the crucial clinical applications of bilirubin testing in diagnosing jaundice and assessing liver function.

Bilirubin Basics: Learn what bilirubin is, where it comes from (heme catabolism), and why it's important to measure. [00:00]
Heme Breakdown: A detailed look at how hemoglobin breaks down into heme and globin. [00:09]
Unconjugated vs. Conjugated Bilirubin: Understand the difference between water-insoluble unconjugated bilirubin and water-soluble conjugated bilirubin. [02:29, 04:49]
Bilirubin Transport and Processing: Follow the journey of bilirubin from the spleen to the liver, where it's conjugated for excretion. [02:13, 04:27]
Clinical Significance: Discover how direct and indirect bilirubin levels help diagnose different types of jaundice and liver problems. [04:56, 05:30]
Pre-hepatic causes: Elevated unconjugated bilirubin (e.g., drug-induced hemolysis, splenomegaly). [05:49, 06:44]
Hepatic causes: Elevated conjugated and unconjugated bilirubin (e.g., hepatitis, cirrhosis). [07:23, 07:37]
Post-hepatic causes: Elevated conjugated bilirubin (e.g., bile duct obstruction). [08:00, 08:19]
Calculating Indirect Bilirubin: Learn the simple calculation to determine indirect bilirubin levels. [09:36, 09:56]
Direct Bilirubin Estimation Procedure: A step-by-step guide to the modified Jendrassik and Groth method. [11:07, 17:38]
Clinical Interpretation of Direct Bilirubin: Understand what elevated direct bilirubin levels might indicate. [18:22]
Practical Instructions: The video provides instructions for performing the experiment. [19:33, 20:00]
Keywords: Bilirubin, direct bilirubin, indirect bilirubin, jaundice, liver function, liver disease, heme, hemoglobin, biochemistry, Jendrassik-Groth, liver, hemolysis, bile duct obstruction.

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TRIPURA SANTINIKETAN MEDICAL COLLEGE
Real Class room Demonstration/Lecture On: (BIOCHEMISTRY) DIRECT BILIRUBIN ESTIMATION AND INDIRECT BILIRUBIN ESTIMATION
BY- DR. KARAN PAL SINGH
(MBBS Batch: 2024- 2025)
Conducted on:- 13-05-25