How to clean a C18 column?

🔬 In this video guide, we explore the necessary techniques for maintaining the efficiency of your C18 column in chromatography. Our expert tips help identify column issues and offer practical cleaning solutions.

🌐 Highlights of the Article:

Identifying Column Issues: Learn how to detect and prevent permanent damages to your HPLC column.

Dealing with Dirty or Clogged Frits: Discover the reasons behind frit clogging and a controversial yet effective cleaning method.

Comprehensive Cleaning Steps: Follow our step-by-step process, starting with flushing with water, followed by using 100% organic solvents, to thoroughly clean your C18 column.

Summary and Best Practices: Gain insights into the overall cleaning process and learn how to effectively remove various compounds without damaging the column.

👩‍🔬 Whether you're a seasoned chromatography professional or new to the field, this article is a must-read to ensure the longevity and efficiency of your C18 columns. Check out the full article for in-depth information and expert advice.

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