Скачать или смотреть The Cholesterol Controversy: Menopausal and statins | Felice Gersh, MD and Leah Vachani

In this Women Aging Powerfully Summit interview, Dr. Felice Gersh breaks down why cholesterol often spikes during perimenopause and menopause by highlighting estradiol’s central role in regulating cholesterol synthesis, transport, and clearance. She also compares the mechanisms of statins versus hormone replacement therapy, discusses natural and lifestyle-based alternatives, outlines key blood tests to monitor, and explains gender-specific cardiovascular risks and prevention strategies.

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00:00 Introduction
02:00 Why cholesterol rises in perimenopause & menopause
03:00 Estradiol’s role in systemic metabolism
06:00 Statins vs. estradiol regulation of HMG-CoA reductase
08:00 Lipoproteins, receptors & cholesterol transport
12:00 Oxidation of cholesterol & plaque formation
16:00 Hormone replacement therapy for cholesterol health
19:00 Uncoupling reproduction from hormones
23:00 Diet, fiber & natural alternatives (e.g., bergamot)
28:00 Essential lipid & inflammation blood markers to request
33:00 When to consider statins for women
38:00 Male vs. female cardiovascular disease differences
44:00 Key takeaways for holistic health management
54:00 Closing remarks & Dr. Gersh’s resources