Скачать или смотреть Transcription in eukaryotes | Elongation | Termination | RNA processing |Capping | Tailing |Splicing

Eukaryotic Transcription

Steps in Eukaryotic Transcription

Initiation

Elongation

Termination.

Initiation

Eukaryotes require several other proteins, called transcription factors, to first bind to the promoter region and then help recruit the appropriate polymerase. The completed assembly of transcription factors and RNA polymerase bind to the promoter, forming a transcription pre-initiation complex (PIC).
Elongation
Following the formation of the preinitiation complex, the polymerase is released from the other transcription factors, and elongation is allowed to proceed as it does in prokaryotes with the polymerase synthesizing pre-mRNA in the 5′ to 3′ direction.
Termination
The termination of transcription is different for the different polymerases.
Post-Transcriptional Modification

Capping: Capping is the process of adding a 7-methylguanosine cap to the 5’ end of the primary transcript by phosphate linkage.

Tailing: Tailing, also known as polyadenylation, is the process of cleavage of the 3’ end and addition of adenylate residues to the same end of the pre-mRNA. 

Splicing: The removal of the non-coding sequences (known as introns) and the reattachment of the coding sequences into a continuous molecule is the process of splicing.

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QUERIES SOLVED
Define Transcription
What are the steps in transcription?
Explain the process of transcription in eukaryotes
Explain RNA processing
Explain splicing

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