Скачать или смотреть Fundamentals of Genomic Medicine

Mohammad Mobashir defined genomic markers as identifiable DNA sequences used to track inheritance and associate variations with diseases, emphasizing their required qualities like high sensitivity and specificity, and their core features including molecular basis and clinical relevance. Mobashir discussed various types of genomic biomarkers, such as Single Nucleotide Polymorphisms (SNPs) and Structural Variants (SVs), along with identification methods including Next-Generation Sequencing (NGS) and their applications in pharmacogenomics and personalized medicine. The advantages of these biomarkers, such as high specificity and applicability for early detection, and the limitations, including the need for advanced bioinformatics and ethical concerns, were also highlighted by Mohammad Mobashir.
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