Скачать или смотреть Repeated IVF failures? Here's what to do next

Repeated implantation failure is one of the most emotionally exhausting challenges faced during IVF treatment. It occurs when embryos of good quality are transferred into the uterus across multiple cycles, yet implantation does not occur. While often dismissed as “bad luck,” implantation failure is rarely random and usually has an underlying biological cause.

One of the most common contributors is embryo-related factors, particularly chromosomal abnormalities. Even embryos that appear healthy under the microscope may carry genetic errors that prevent successful attachment and development.

The uterine environment plays a crucial role in implantation. Conditions such as thin endometrial lining, fibroids, polyps, intrauterine adhesions, or chronic inflammation can interfere with the embryo’s ability to implant. Many of these issues remain undetected without targeted evaluation.

Hormonal balance is equally critical. Inadequate progesterone support, thyroid dysfunction, insulin resistance, or immune-related factors can disrupt the implantation window and reduce success rates, even when embryo quality is good.

Lifestyle and metabolic factors also have a silent but significant impact. Increasing maternal age, obesity, smoking, high stress levels, poor sleep quality, and sedentary habits can negatively affect endometrial receptivity and implantation potential.

After repeated implantation failures, advanced diagnostic tools such as hysteroscopy, endometrial receptivity analysis (ERA), immune testing, and genetic testing of embryos help identify the precise cause. These insights allow fertility specialists to move away from repetitive protocols and toward highly personalized treatment strategies.

Once the root cause is identified, treatment may involve improved uterine preparation, protocol modification, optimized hormonal support, immune regulation, or refined embryo selection. Success often lies not in repeating IVF cycles, but in refining the approach.

Repeated implantation failure does not mean the end of fertility treatment. It signals the need for deeper investigation, individualized care, and evidence-based decision-making.

Seeking help for IVF failures? Book your consultation with our Ferty9 experts today by calling + 91 9390 501 362