Causes of Hyperlipidemia (Hypercholesterolemia and Hypertriglyceridemia)

Causes of Hyperlipidemia (Hypercholesterolemia and Hypertriglyceridemia):

Primary Causes:

1. Genetic factors (familial hypercholesterolemia)
2. Diet high in saturated fats, cholesterol, and calories
3. Obesity
4. Physical inactivity
5. Age (increases with age)

Secondary Causes:

1. Diabetes mellitus
2. Hypothyroidism
3. Kidney disease (nephrotic syndrome)
4. Liver disease (cirrhosis)
5. Certain medications:
Steroids
Beta-blockers
Thiazide diuretics
Estrogen therapy
6. Other medical conditions:
Polycystic ovary syndrome (PCOS)
Cushing's syndrome
Acromegaly

Hypertriglyceridemia-specific causes:

1. High carbohydrate diet
2. Alcohol consumption
3. Estrogen therapy
4. Certain medications:
Tamoxifen
Corticosteroids
Retinoic acid

Hypercholesterolemia-specific causes:

1. Dietary cholesterol
2. Saturated and trans fats
3. Familial hypercholesterolemia
4. Apolipoprotein E deficiency

Other factors:

1. Stress
2. Sedentary lifestyle
3. Smoking
4. Family history

Note: This is not an exhaustive list, and other factors may contribute to hyperlipidemia. A healthcare professional can help determine the underlying cause of hyperlipidemia in an individual.

#Hyperlipidemia