Exploring the Impact of the Gut Microbiome on Your Health | S. Devkota | The Proof Podcast EP

Recent years have seen a surge in interest in the gut microbiome, an intricate area of research that is only just beginning to reveal its vast implications for our health. Even though we are just at the outset of fully understanding this complex ecosystem, there have already been exciting discoveries that set science on the path to understanding the role of the gut microbiome more comprehensively. In Episode #267, I’m joined by Dr Suzanne Devkota for a deep dive into the gut microbiome’s influence on inflammatory and metabolic diseases.

👇 Visit The Proof website for the full show notes and supporting studies. 👇 https://theproof.com/podcast/

Dr Suzanne Devkota stands at the forefront of microbiome research. As the Director of Microbiome Research at Cedars-Sinai Medical Center and an appointee at the University of California-Los Angeles Department of Medicine, she deepens our understanding of the gut microbiome's role in inflammatory and metabolic diseases. Her research, published in highly esteemed journals like Nature, sheds light on the increasing prevalence of diseases such as IBD, diabetes, and food allergies. Currently, she explores the fascinating sphere of pathobionts and the translocation of gut bacteria. With a strong academic background from the University of Illinois and The University of Chicago, Dr Devkota has become a significant figure in this rapidly emerging field. Her accomplishments include multiple NIH R01 grants and the prestigious NIH Director’s Pioneer Award.

In this episode, we discuss:
00:00 - Intro
02:13 - The evolving field of microbiome research
09:32 - Gut microbe on social media
12:48 - Microbiome definition
13:55 - Why the focus on gut bacteria?
16:02 - Differences in Microbes
18:45 - Microbial shifts and adaptations
21:35 - Microbes perturbations
24:19 - Human microbiome in evolution
28:13 - Healthy microbiome and diversity
34:09 - Is the microbiome the sole driver of metabolic diseases? 
41:33 - Dietary patterns and FODMAP intolerance
49:41 - Saturated fat and gut health
58:25 - Microbiome metabolites and heart disease risk
1:02:52 - Inflammatory bowel disease (IBD) and dysbiosis
1:13:13 - Food additives
1:16:12 - Supporting the microbiome in IBD
1:18:01 - Microbiome's interaction with fat cells
1:30:35 - Short-chain fatty acids and appetite regulation
1:32:35 - Practical tips for nourishing a healthy gut
1:39:52 - Microbiome's interaction with Polyphenols
1:40:25 - On supplements and fermented foods
1:47:31 - Factors affecting gut health beyond nutrition
1:51:19 - Outro

Connect with Dr Suzanne Devkota:

- Instagram:   / suzannedevkota  
- Twitter:   / suzanne_devkota  
- Website: http://www.devkotalab.com/thelab

If you have any additional questions you would like answered in the future, let me know in the comments.

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Enjoy, friends.

Simon

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