Скачать или смотреть Episode 305: Pharmacology 101: Nitrosoureas

"A couple of things I think are really important when you look at this class of drug: It developed by a concerted effort in cancer drug development to look at new agents that would be effective based on the mechanism. And then once they found a drug in this class that was beneficial, they further modified it to try to get better efficacy and less toxicity," Rowena "Moe" Schwartz, PharmD, BCOP, FHOPA, professor of pharmacy practice at James L. Winkle College of Pharmacy at the University of Cincinnati in Ohio, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about the nitrosoureas drug class.


Music Credit: "Fireflies and Stardust (http://www.incompetech.com/) " by Kevin MacLeod


Licensed under Creative Commons by Attribution 3.0


The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of NCPD by the American Nurses Credentialing Center's Commission on Accreditation.


Learning outcome: Learners will report an increase in knowledge related to nitrosourea administration.


Episode Notes


• The NCPD activity for this episode has expired, but you can still earn NCPD through many other ONS Podcast episodes. Find a full list of opportunities (https://www.ons.org/education-hub/ons...) .

• Oncology Nursing Podcast episodes:

• Episode 286: Pharmacology 101: Alkylating Agents (https://www.ons.org/podcasts/episode-...)

• Episode 288: Pharmacology 101: Antimetabolites (https://www.ons.org/podcasts/episode-...)

• Episode 296: Pharmacology 101: Anthracyclines and Other Antitumor Antibiotics (https://www.ons.org/podcasts/episode-...)

• Episode 299: Pharmacology 101: Plant Alkaloids (https://www.ons.org/podcasts/episode-...)


• ONS Voice article: The Oncology Nurse's Role in Oral Anticancer Therapies (https://voice.ons.org/news-and-views/...)

• ONS courses:

• ONS/ONCC Chemotherapy Immunotherapy Administration Certificate™ (https://www.ons.org/courses/onsoncc-c...)

• ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ (https://www.ons.org/courses/ons-funda...)


• ONS books:

• Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (https://www.ons.org/books/chemotherap...) (second edition)

• Clinical Guide to Antineoplastic Therapy: A Chemotherapy Handbook (https://www.ons.org/books/clinical-gu...) (fourth edition)

• Safe Handling of Hazardous Drugs (https://onf.ons.org/books/safe-handli...) (fourth edition)


• Clinical Journal of Oncology Nursing article: Primary Central Nervous System Lymphoma: Treatment and Nursing Management of Immunocompetent Patients (https://onf.ons.org/cjon/25/4/primary...)

• Oncology Nursing Forum article: ONS Guidelines™ to Support Patient Adherence to Oral Anticancer Medications (https://onf.ons.org/ons-guidelines-su...)

• ONS Oral Anticancer Medication Learning Library (https://onf.ons.org/learning-librarie...)

• ONS Oral Adherence Video (https://www.ons.org/clinical-practice...)

• National Institute for Occupational Safety and Health: Hazardous Drugs in Healthcare Settings (https://www.cdc.gov/niosh/topics/hazd...)


To discuss the information in this episode with other oncology nurses, visit the ONS Communities (http://communities.ons.org/) .


To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library (https://www.ons.org/learning-librarie...) .


To provide feedback or otherwise reach ONS about the podcast, email [email protected] (mailto:[email protected]?subject=Website%20feedback%20from:%20Oncology%20Drug%20Reference%20Sheet:%20Trilaciclib) .


Highlights From This Episode


"With the nitrosoureas, there's something really interesting because there's another mechanism that has been identified. And that is that when you put these nitrosoureas in the body, they break down i...