Letrozole is one of the most commonly prescribed medications for ovulation induction, especially in women dealing with PCOS, irregular periods, or anovulation. It has become a preferred choice compared to Clomiphene (Clomid) for many fertility specialists due to its higher ovulation and pregnancy success rates. In this video, we explain what Letrozole is, how it works, who benefits the most, side effects, timing, success rates, and important precautions.
💡 What is Letrozole?
Letrozole belongs to a group of medicines called Aromatase Inhibitors. It lowers estrogen levels briefly, which triggers the brain to increase FSH (Follicle-Stimulating Hormone). This stimulates the ovaries to develop mature follicles, leading to natural ovulation.
⭐ Benefits of Letrozole for Ovulation Induction
Effective in women with PCOS
Higher ovulation and live-birth rates compared to clomiphene
Lower risk of ovarian hyperstimulation
Lower risk of multiple pregnancies (twins)
Suitable for women who failed to ovulate with Clomid
🔍 Who Needs Letrozole?
Your doctor may recommend Letrozole if you have:
PCOS
Irregular or absent periods
Unexplained infertility
Ovulation problems
Prior failure to respond to Clomid
⏱️ How Letrozole Works in a Cycle
Letrozole is usually taken for 5 days early in the menstrual cycle, after which follicles are monitored through ultrasound. Once the follicle reaches maturity, natural ovulation follows, or a trigger injection may be used as advised by your doctor.
📈 Success Rates
Success depends on age, ovarian reserve, and underlying cause, but Letrozole has shown:
70–85% ovulation rate
20–25% pregnancy rate per cycle
Better outcomes in PCOS compared to Clomid
⚠️ Side Effects (Usually Mild)
Headache
Fatigue
Hot flashes
Dizziness
Mild bloating
Most women tolerate Letrozole well, and side effects are temporary.
🔔 Important Tips
Always use Letrozole under a fertility specialist’s guidance
Follicle scanning is important
Take a healthy diet and maintain weight
Do not self-medicate
This video is your complete guide to understanding Letrozole for ovulation induction — from mechanism to monitoring, benefits, risks, and real expectations.
#Letrozole #OvulationInduction #PCOS #FertilityTreatment #Infertility
Keywords
Letrozole, ovulation induction, PCOS ovulation, infertility treatment, letrozole success
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CHAPTERS & VIDEO TIME-STAMPS:
00:00 - Introduction To ovulation inductions and Letrozole & clomiphene citrate
01:02 - What is Letrozole? Mechanism of action of Letrozole
01:53 - CLOMIPHENE citrate for ovulation stimulation
03:07 - Indications of Letrozole for ovulation stimulation
04:07 - Disadvantages of Clomiphene citrate
06:03 - Advantages of Letrozole versus Clomiphene citrate
06:54 - How to use Letrozole for ovulation induction?
09:22 - Letrozole with FSH or HMG
10:02 - Multifollicular ovulation with Letrozole
12:21 - Pregnancy rate with Letrozole
14:18 - Co-prescriptions with letrozole
17:18 - Letrozole for breast cancer, adenomyosis, heavy menstrual bleeding, endometriosis
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