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Heart Health: From Risk Factors to Disease Management
If we always take the cancer paradigm, right? If you have cancer risk factors, that's one thing. But once you develop the cancer, nobody anymore cares about your risk factors. They care about the cancer. How big is the cancer? Where's the cancer located? What type of cancer is it? What stage is it, right? So, we want to do the exact same paradigm with atherosclerosis, right? You know, you might use risk factors to identify someone to look at, but once you define the disease, the risk is the disease expression. It's no longer the risk factors of having the disease, right?
So, that's one thing cardiology has failed to do is that we're all focused on the risk factors of the disease that are population based. The, phenotypic expression of the atherosclerosis tells you the risk, and the more plaque there is, the riskier it is, the more of the low density and non calcified plaque, the riskier it is. And sometimes that's very independent of the traditional risk factors that we think of.

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