Diane Davis' Story: Ovarian Cancer Survivor

In January 2017, Diane's gynecologic oncologist, Dr. Christopher Darus, discovered a softball size tumor in her ovary that had metastasized into the surrounding tissues and into her bowels. She had Stage IIC ovarian cancer. Dr. Darus removed her ovaries and 18 inches of her sigmoid colon because of tumor involvement and immediately started Diane on a standard chemotherapy regiment.

Dr. Darus began searching for clinical trials and sent her tumor biopsy to Caris for molecular testing to see if there was anything they were missing that only molecular profiling would show.

Caris’ molecular profiling confirmed an MSI-H finding, but it also revealed BRCA2, which was a surprising discovery, and another biomarker target they could exploit for future therapies. It opened up new treatment options for Diane that would not have been known before.

Diane had an immediate and remarkable response to immunotherapy with symptoms diminishing and feelings of discomfort retreating. She started the immunotherapy in June 2017 and in August, three months later, her tumor had disappeared and the cancer had shrunk considerably in her lymph nodes.

Learn more about Caris molecular profiling: https://www.carislifesciences.com/

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