Dr. Agam Dhawan is a board-certified Child, Adolescent & Adult Psychiatrist and PMHNP Coach. He logs on LIVE to discuss the top questions from the audience:
00:11 – Depakote (valproic acid): Uses, mechanism, and dosing
05:01 – Weight-based dosing and serum level targets for Depakote
07:19 – Depakote DR vs ER formulations and dose conversion
09:02 – Depakote side effects: Hair thinning, weight gain, sedation
10:00 – Hepatic metabolism, PCOS risk, contraindications
11:00 – Monitoring labs for Depakote and pregnancy risks
13:02 – Valproate vs lithium in mixed states and rapid cycling
16:34 – Carbamazepine (Tegretol): Mechanism, uses, and kindling theory
18:02 – Carbamazepine dosing, autoinduction, and serum levels
19:44 – Side effects and risks: Rash, hyponatremia, SJS
21:29 – Drug interactions and key contraindications
22:57 – Half-life, pharmacokinetics, and patient selection
26:25 – Oxcarbazepine (Trileptal): More tolerable but weaker than Tegretol
27:26 – No autoinduction, dosing strategy, and renal adjustment
29:03 – Unique side effects: Severe hyponatremia, dizziness
30:04 – Monitoring needs and typical pediatric use
34:22 – Alprazolam (Xanax): Mechanism, dosing, and rapid onset
36:03 – Benzodiazepine receptor function and GABA enhancement
37:20 – Abuse potential, short half-life, and rebound anxiety
39:00 – Xanax risks: Withdrawal, disinhibition, respiratory depression
43:37 – Lorazepam (Ativan): Uses, dosing, and liver-safe profile
45:48 – Ativan vs Xanax vs Klonopin comparison
47:28 – Onset, duration, metabolism, and clinical indications
51:17 – Clonazepam (Klonopin): Longer-acting benzo for maintenance
52:58 – Indications: Panic, insomnia, TD, agitation, RLS, etc.
54:22 – Onset, half-life, potency comparison, tapering guidance
57:02 – Clonazepam vs lorazepam for social anxiety
1:04:28 – Diazepam (Valium): Long-acting, rapid-onset benzo
1:06:03 – Valium use for tapering, muscle spasms, alcohol withdrawal
1:07:03 – Stacking risks and when Valium is a good option
1:09:18 – Temazepam (Restoril): Sleep-only benzo for onset + maintenance
1:13:35 – Temazepam dosing, metabolism, and safety in hepatic patients
1:14:50 – Avoiding complex sleep behaviors and rebound insomnia
1:19:09 – Comparing benzos: Potency, half-life, onset, and clinical use
1:22:51 – Recap: High-yield benzo facts and therapeutic strategy
1:23:22 – End of session: Summary and next steps
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