Cancer Survivor Story: Finding Treatment After Relapse | Beth's Multiple Myeloma Story (4 of 5)

Beth was just 29 years old and the mother of two young kids when she was diagnosed with multiple myeloma. After first-line treatment of radiation, chemotherapy, and a successful stem cell transplant, she lived 12 years with no sign of myeloma.

In this segment, Beth focuses on what treatments she took for her multiple myeloma after it had become refractory to the 3 main classes of drugs used to treat myeloma. Not wanting to pursue CAR T-cell therapy, she describes her experiences with belantamab mafodotin (Blenrep), which did not work for her, and the combination of selinexor (XPOVIO), bortezomib (Velcade) and dexamethasone, which has been successful. See below for time codes.

Our 5 part series:
Video 1: Getting Diagnosed
Video 2: Getting Cancer Care in a Small Town
Video 3: The Relapse
THIS VIDEO: Relapsed/Refractory Cancer Treatment + Newest Options
Video 5: Living Life with Myeloma

Full story & transcript →https://www.thepatientstory.com/cance...

Thank you to Karyopharm for its support of our educational program. The Patient Story has full editorial control of our content. The interview has been edited only for clarity.

TIME CODES:

Part 1: CAR T-Cell Therapy
(00:56)How did your oncologist describe the CAR T-cell therapy option?

Part 2: Belantamab mafodotin (BLENREP)
(4:03) How was your experience with belantamab mafodotin (BLENREP)? What were the side effects?
(7:41)What helped with the BLENREP side effects?
(8:39)What was the Risk Evaluation and Mitigation Strategy (REMS) program for the eye problems?

Part 3: Selinexor + Bortezomib + Dexamethasone Combination (SVd)
(11:02) How did you learn of this treatment option?
(12:05)What was the status of your myeloma?
(14:08) Describe the selinexor + velcade + dexamethasone (SVd) regimen
(14:51) Describe the selinexor, bortezomib, dexamethasone combination side effects
(16:51)What has helped you manage the side effects, including adjusting the dose?
(18:19)The “1-2-3” anti-nausea medication plan
(20:35)What’s the real impact of finding a new treatment that finally works for you?

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