Скачать или смотреть EEG Monitoring Approaches to Predict Learning and Memory Changes in Early Alzheimer’s Disease

A major goal of Alzheimer’s disease research is to find factors that may be predictive of later cognitive decline. Environmental factors such as dietary deficiency or exposure to toxins may have little detectable impact in young and middle-aged brains yet still accelerate disease pathways to contribute to earlier onset of neurodegenerative disease over time. Understanding the mechanisms involved could lead to new preventative strategies to slow the onset of cognitive decline or may suggest new pathways for pharmacological interventions in later life.

During this webinar, Dr. Harrison discusses how even seemingly mild changes in neural signaling can be detected through altered EEG activity and correlated with poorer performance on tasks of learning and memory. In addition, she demonstrates how vitamin C deficiency and exposure to toxins can impact glutamate uptake and clearance. Using mouse models of beta-amyloid aggregation and wild-type controls at different ages, the Harrison lab uses molecular biology, behavioral and electrophysical techniques to understand triggers for onset of cognitive decline even in the absence of high levels of classical Alzheimer’s disease neuropathology.

Key Topics Include:
Demonstrate that small changes in neural activity are correlated with significant changes in behavior
Demonstrate the utility of using long-term measurement of EEG in the home-cage rather than smaller snapshots of neural activity
Demonstrate how different factors of the exposome – diet and environmental toxins – can impact onset of Alzheimer’s disease and cognitive decline

To learn more, go to:
https://insidescientific.com/webinar/...