Скачать или смотреть Lecture On Immunoprophylaxis & Vaccines: Active vs. Passive Immunity | MBBS

In this session, recorded for the 2024-2025 Batch at Santiniketan Medical College & Hospital, we explore the historical journey and the biological mechanisms of vaccination. This lecture is essential for medical students mastering Microbiology and Preventive & Social Medicine (PSM), providing a clear framework for active and passive immunization strategies.

In this video, you will explore:

1. The History & Impact of Vaccination [00:24]:

From Edward Jenner’s Smallpox breakthrough in 1796 to Louis Pasteur’s Rabies vaccine [02:55].

How vaccines have exponentially increased human life expectancy by eradicating infectious diseases [01:27].

2. Principles of Immunoprophylaxis [06:13]:

Defining Active vs. Passive Immunity [08:26].

Herd Immunity Explained: Understanding the mathematical models and population thresholds required to prevent outbreaks [14:40].

3. Types of Vaccines (Classification) [18:42]:

Live Attenuated Vaccines: Why they mimic natural infection and usually only require a single dose (BCG, OPV, MMR) [20:08].

Inactivated (Killed) Vaccines: Safety in immunocompromised patients and the need for boosters (Pertussis, Rabies, IPV) [21:43].

Subunit & DNA Vaccines: Modern approaches like Hepatitis B surface antigen and mRNA technology used during COVID-19 [25:54].

Toxoids: Neutralizing bacterial toxins in Diphtheria and Tetanus [24:36].

4. Clinical & Logistics Considerations [29:54]:

The Cold Chain: Maintaining biological integrity from factory to patient [31:00].

Vaccine Vial Monitors (VVM): How to read heat-exposure indicators on vaccine amples [32:17].

5. National Immunization Schedule (India) [33:03]:

A complete walkthrough of vaccines given at birth, 6 weeks, 10 weeks, 14 weeks, and beyond [33:38].

Vaccination for pregnant women and high-risk occupations (veterinarians and healthcare workers) [35:34].

Key Learning Outcomes:

Differentiate between humoral and mucosal immunity (IgG vs. IgA) provided by various vaccines [23:40].

Identify contraindications for live vaccines in pregnancy and immune deficiency [20:58].

Understand the role of Adjuvants in enhancing immune response [14:02].


SANTINIKETAN MEDICAL COLLEGE & HOSPITAL
Real Classroom Demonstration/Lecture
On: MICROBIOLOGY by Dr. Sourav Pal
(MBBS Batch: 2024-25)
Conducted on: 29-01-26