Скачать или смотреть Hippocampal long-term potentiation in response to tinnitus is rats, Grace Kelly

Tinnitus occurs when sound is heard in absence of an external sound stimulus. This common condition can lead to insomnia, anxiety, and depression. Tinnitus is thought to be caused by the failure of a “noise cancellation” system in the brain to prevent unwanted sound from being consciously perceived. To further understand how this occurs, this project investigated the ability of neurons to communicate with each other in a specific brain region called the hippocampus, which is part of the “noise cancellation” system, in an animal model of tinnitus. In this animal model, tinnitus was induced by exposing the animals to acoustic trauma. It was found that animals that received acoustic trauma had an increased strength of communication in the hippocampus compared to the control. This suggests that increased neural communication inside the hippocampus may contribute to the failure of the cancellation of tinnitus sound in the brain.