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Cleveland Cavaliers vs. New York Knicks – Season Opener Preview, Picks & Predictions

The Cavs head to Madison Square Garden as 1.5-point road favorites against the Knicks, with a total of 227.5. The injury report is shaping the line: Darius Garland (toe) and Max Strus (foot) are out, De’Andre Hunter (knee) is questionable. For the Knicks, Josh Hart (back) and Mitchell Robinson (ankle) are out, while Karl-Anthony Towns (quad) is questionable.

Munaf Manji and Mackenzie Rivers break down the matchup. Mackenzie sides with the Cavs, citing their offensive turnaround last season under Kenny Atkinson, replacing JB Bickerstaff’s stagnant system. Cleveland’s attack was historic by points per possession, and though they fell short in the playoffs, they return nearly the same roster minus Garland. The Knicks, meanwhile, enter a new era under Mike Brown, moving away from the “Tibbs grind” but still plagued by injuries.

Mackenzie notes that last year the market rated the Cavs four points better than the Knicks, supported by their 4-0 record (both straight up and ATS) in that span, winning by an average of 14. He believes Garland’s absence is worth about 1.5 points, not enough to justify the swing toward New York, especially given the Knicks’ frontcourt issues. He bet Cavs +2.5 before the injury news and still likes them despite the shift.

Munaf echoes that sentiment, emphasizing rebounding concerns for New York without Robinson or Towns. Facing Cleveland’s Jared Allen and Evan Mobley, the Knicks could struggle to contain second-chance points. He expects Donovan Mitchell to shine in a statement game after last year’s playoff exit, predicting a strong scoring night. Munaf also questions how Mike Brown’s rotations will look early, with Jordan Clarkson adding offensive spark but defensive liability.

On totals, Mackenzie slightly leans Over 227.5, noting most Game 1s trend that way and the Cavs’ offense drives his handicap. Munaf agrees but highlights defensive fatigue could become a long-term issue for the Knicks if they rely heavily on their top rotation early. He likes Mitchell’s points prop and would consider Towns’ rebounds if he’s cleared, recalling his dominance on the glass last season when Robinson was out.

Both analysts agree: the Cavs have the deeper, more cohesive lineup and the offensive edge to spoil the Knicks’ home opener. Cleveland’s continuity and frontcourt strength should overpower New York’s undermanned rotation.

Picks: Cavs -1.5; Lean Over 227.5; Player Props – Mitchell points Over, Towns rebounds Over (if active).

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