Скачать или смотреть Immune Check Point Induced Adrenalitis and Hypophysitis

These sources collectively discuss *immune-related adverse events (irAEs)**, specifically focusing on **endocrine complications* arising from *immune checkpoint inhibitor (ICI) therapy* for cancer. They provide an *overview of common endocrine irAEs**, such as **thyroid disorders, hypophysitis, primary adrenal insufficiency, and diabetes mellitus**, detailing their **incidence, typical onset, and clinical presentations**. The texts also outline **diagnostic approaches, treatment strategies (including the role of hormone replacement and the limited use of high-dose glucocorticoids)**, and emphasize the **importance of multidisciplinary collaboration between oncologists and endocrinologists* for optimal patient management. Additionally, some sources touch upon the **correlation between developing irAEs and improved cancer treatment outcomes**, as well as the **often permanent nature of these endocrine dysfunctions**.