#82 Nick Hiebert - Seed Oils, Saturated Fat, & Cardiovascular Disease

In this episode of The Muscle Memoirs Podcast, I am joined by Nick Hiebert to discuss how dietary fat relates to cardiovascular health. We cover the science on seed oils, saturated fat, the omega-6/omega-3 ratio, and more.

Nick Hiebert is a nutrition science communicator. He is known for creating in-depth educational content, ranging from nutrient density to saturated fat and cardiovascular disease, and has published some independent meta-analyses on his website. He is also the creator of the Nutri-Dex, a novel nutrition ranking tool.

References
- Reduction in saturated fat intake for cardiovascular disease
https://pubmed.ncbi.nlm.nih.gov/32428...
- The omega-6/omega-3 ratio and cardiovascular disease risk: uses and abuses
https://pubmed.ncbi.nlm.nih.gov/17045...
- What’s the Deal With Seed Oils?
http://hammerawayfitness.com/whats-th...
- Saturated Fat: Cutting Through the Noise
https://thenutrivore.blogspot.com/202...
- Linoleic Acid and Inflammation (An Independent Meta-Analysis of RCTs)
  / linoleic-acid-of-49040624  

Timestamps
00:00 Introduction
03:20 Mechanistic arguments against seed oils: lipid peroxidation and hyperphagia
08:20 Human data
15:50 Relationship between linoleic acid consumption and CVD
17:20 Why shouldn't we rely on the diets of hunter-gatherers to guide public health?
21:55 The optimal diet for humans is probably heavily synthetic
26:25 Omega-6/omega-3 ratio
32:25 Does the data support limiting saturated fat intake?
40:30 Caveats to saturated fat unfavorably altering blood lipids
42:40 The effect of replacing saturated fat with refined grains
44:25 Is the problem a low polyunsaturated fat intake rather than saturated fat?
47:30 Explaining meta-analyses that show a null result of saturated fat intake on CVD
52:45 Differences in saturated fat intake between populations and the threshold effect
55:50 Saturated fat intake in Finland
58:05 The relationship between saturated fat intake and all-cause mortality

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