Introduction to Metagenomics

This is the first module of the Analysis of Metagenomic Data 2018 workshop hosted by the Canadian Bioinformatics Workshops at the Ontario Institute for Cancer Research. This session is by William Hsiao from the University of British Columbia.

Table of Contents:

00:59 - Course overview
04:53 - General Learning Objectives
06:06 - Learning objectives of Module 1
07:14 - Defining Metagenomics
10:08 - The big picture
11:47 - Why metagenomics?
14:26 - Turkey Microbiome
15:18 - Turkey Microbiome –why do we care?
16:25 - Turkey Microbiome – can impact human
17:01 - From Turkey to Turkish Drink
17:02 - Turkey Microbiome – can impact human
17:06 - From Turkey to Turkish Drink
18:44 - Most of you is not you….
19:53 -
20:16 - Sequencing technologies
21:00 - Sequencing Run Capacity
21:01 - Sequencing technologies
22:12 - Sequencing Run Capacity
22:21 - What can Microbiome Studies Answer?
23:17 - What’s in the microbiome?
23:23 - What can Microbiome Studies Answer?
23:26 - What’s in the microbiome?
24:00 - What functions are present in the microbiome?
26:26 - What does the microbiome correlate with?
27:59 - How will the microbiome respond?
30:41 - A Brief History of Metagenomics and Things Like It
30:54 -
31:43 - Staden (1979)
31:44 -
32:01 - Staden (1979)
33:17 -
33:19 -
33:28 -
33:29 -
33:53 -
34:20 -
35:30 -
36:38 -
36:48 - Major concerns in metagenomic analysis
36:49 -
37:39 - Major concerns in metagenomic analysis
37:47 - Data Quality
41:05 - Minimal Metadata about a Microbiome Experiment
43:44 - Comparability / Reproducibility
45:34 - Linkage and resolution
47:03 - Taxonomy and OTUs
48:14 - Functional annotation problems
49:56 - Resources
50:03 - 16S
50:33 - Genomes
51:30 - “Metagenomes”
52:30 - Function
53:49 -