Hemolytic Anemia | Hematology | Part 2🩺

#Anemia #HemolyticAnemia #TypesofAnemia #hematology

Hemolytic Anemia | Hematology | Part 2🩺

Like this video? Sign up now on our website at https://www.DrNajeebLectures.com
to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $45 ONLY!

Sign up now on our website at https://members.drnajeeblectures.com/...
---------------------------------------------------------------------------------------------------------------------------
Why sign up for premium membership? Here's why!
Membership Features for premium website members.

1. More than 800+ Medical Lectures.
2. Basic Medical Sciences & Clinical Medicine.
3. Mobile-friendly interface with android and iOS apps.
4. English subtitles and new videos every week.
5. Download option for offline video playback.
6. Fanatic customer support and that's 24/7.
7. Fast video playback option to learn faster.
8. Trusted by over 2M+ students in 190 countries.
---------------------------------------------------------------------------------------------------------------------------
▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬
00:00:00 Differentiation of Hemolysis from normal breakdown of Red Blood Cells
00:02:27 Mechanism of Erythropoietin function and its role in compensation of hemolysis
00:18:43 Increased unconjugated Bilirubin and Jaundice to determine presence of Hemolysis
00:24:24 Increased urobilinogen and dark stools to determine presence of Hemolysis
00:34:03 Increased serum Lactate Dehydrogenase to determine presence of Hemolysis
00:35:09 Decreased serum free Haptoglobin
00:38:48 Review of clinical signs and Laboratory investigations
00:39:05 Increased Reticulocytes to determine increased Erythropoiesis
00:44:27 Slight Macrocytosis to determine increased Erythropoiesis
00:46:06 Polychromasia to determine increased Erythropoiesis
00:47:44 Hypercellular Bone Marrow to determine increased Erythropoiesis
00:48:23 Extravascular Hemolysis
00:50:30 Intravascular Hemolysis
00:56:35 Determining Acute or Chronic nature of Hemolysis
01:00:16 Review of concepts

---------------------------------------------------------------------------------------------------------------------------


Hemolytic anemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). This most commonly occurs within the spleen, but also can occur in the reticuloendothelial system or mechanically (prosthetic valve damage). Hemolytic anemia accounts for 5% of all existing anemias. It has numerous possible consequences, ranging from general symptoms to life-threatening systemic effects. The general classification of hemolytic anemia is either intrinsic or extrinsic. Treatment depends on the type and cause of the hemolytic anemia.

Symptoms of hemolytic anemia are similar to other forms of anemia (fatigue and shortness of breath), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones and pulmonary hypertension.

Symptoms of hemolytic anemia are similar to the general signs of anemia. General signs and symptoms include: fatigue, pallor, shortness of breath, and tachycardia. In small children, failure to thrive may occur in any form of anemia. In addition, symptoms related to hemolysis may be present such as chills, jaundice, dark urine, and an enlarged spleen. Certain aspects of the medical history can suggest a cause for hemolysis, such as drugs, medication side effects, autoimmune disorders, blood transfusion reactions, the presence of prosthetic heart valve, or other medical illness.

Chronic hemolysis leads to an increased excretion of bilirubin into the biliary tract, which in turn may lead to gallstones. The continuous release of free hemoglobin has been linked with the development of pulmonary hypertension (increased pressure over the pulmonary artery); this, in turn, leads to episodes of syncope (fainting), chest pain, and progressive breathlessness. Pulmonary hypertension eventually causes right ventricular heart failure, the symptoms of which are peripheral edema (fluid accumulation in the skin of the legs) and ascites (fluid accumulation in the abdominal cavity).
---------------------------------------------------------------------------------------------------------------------------
Join this channel to get access to perks:
Sign up now on our website at https://members.drnajeeblectures.com/...
   / @doctornajeeb  
Follow us on Facebook :-   / drnajeeb  
Follow us on Instagram :-   / drnajeeblectures