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Researchers at the University of Virginia School of Medicine have identified a key driver of chronic inflammation, known as "inflammageing” and identified as one of the root causes of aging by Lopez Otin and his team.

The study found that chronic inflammation is driven by “improper calcium signaling in the mitochondria of certain immune cells. Mitochondria are the power generators in all cells, and they rely heavily on calcium signaling, but they lose their ability to take up and use calcium with age. This, the researchers show, leads to chronic inflammation responsible for many of the ailments that afflict our later years.”

The UVA health researchers believe that increasing calcium intake should mitigate this problem, but it doesn’t cover all bases because it is the macrophages that stop working properly.

In this case, we would suggest not only increasing dietary sources of calcium like sesame seeds, sardines, non-GMO, organic soy, kale, and seaweed, but also to trigger autophagy through fasting, exercise, improving sleep quality, and consuming spermidine-rich foods like the long fermented soybean dish, natto, tempeh, and shiitake mushrooms.

To learn more, read the full study on Nature Aging by clicking the link under 'recent studies' in our bio.

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