为什么梅毒化验会出现假阳性 郝飞 陆军军医大学第一附属医院

为什么梅毒化验会出现假阳性 郝飞 陆军军医大学第一附属医院
梅毒化验会出现假阳性的原因有以下几点：1、有些人梅毒血清检查阳性，但并非梅毒就是假阳性，假阳性这主要是生物学因素考虑的，很多一些体内的复杂成分可能会影响到检测的过程，造成假阳性，这种发生率总体来讲是比较低的，主要见于一些非梅毒螺旋体特异性的实验，比如TRUST或RPR等；2、老年人会出现假阳性；3、一些孕妇怀孕的过程当中它这种生理性的状态可能会呈假阳性；4、一些特殊的基本状态比如像类风湿关节炎、红斑狼疮或者是其他一些机体组织病，同样也可以出现假阳性，当然还有某些特殊的状态，比如冷球蛋白血症等都可能会出现假阳性。这些都属于非梅毒螺旋体本身所引发的阳性结果，是血清当中某些复杂的成分，比如像类风湿因子特别高的情况下也可以引起假阳性的过程。怎么去区别这一类是假阳性，我们主要是看梅毒螺旋体的确诊试验是否阳性，如果梅毒螺旋体的确诊是阴性的而单纯表现的梅毒螺旋体是阳性，通常这种情况下要考虑假阳性，当然我们也可以进一步通过病史的询问有没有梅毒病史的过程等去排除。我这里特别强调的梅毒的假阳性，发生率是很低的，如果出现假阳性一定要认真地排除是否真没有患上梅毒。

Why does syphilis test appear false positive
There are several reasons for false-positive syphilis test: 1. Some people have positive syphilis serum test, But not syphilis, False positive is mainly considered by biological factors, Many complex components in the body may affect the detection process, False positive, Generally speaking, the incidence is relatively low, It is mainly found in some non Treponema pallidum specific experiments, Such as trust or RPR; 2. The elderly will appear false positive; 3. Some pregnant women may be false positive in this physiological state during pregnancy; 4. Some special basic conditions, such as rheumatoid arthritis, lupus erythematosus or other diseases of the body tissue, False positives can also occur, Of course, there are some special states, For example, cold globulinemia may appear false positive. These are all positive results caused by non Treponema pallidum itself, It's a complex component of serum, For example, when rheumatoid factor is very high, it can also cause false-positive process. How to distinguish the false positive, We are mainly looking at the positive diagnosis test of Treponema pallidum, If the diagnosis of Treponema pallidum is negative and the simple manifestation of Treponema pallidum is positive, In general, false positives should be considered, Of course, we can further exclude syphilis through the process of history inquiry. The false positives of syphilis that I'm highlighting here, The incidence is very low, If there is a false positive, we must seriously rule out whether there is no syphilis.