Скачать или смотреть Synthetic Antibodies

Molecular recognition processes are involved in almost every aspect of biological interactions, ranging from enzyme-substrate recognition up to DNA replication and translation.

The very same recognition processes are exploited for in vitro diagnostics and therapeutic applications by using biologically-derived materials such as antibodies and natural receptors, which unfortunately are hindered by several drawbacks, not least their expensive production and poor stability.

It is not surprising, then, that a considerable portion of nowadays research is directed towards the investigation and production of man-made materials capable of mimicking these molecular recognition processes.

Amongst these materials, molecular imprinting polymers (MIPs) represent generic alternatives to antibodies and receptors in diagnostics and separation.

This talk by Dr Alessandro Poma covers the fundamentals of the technology, and discusses the major breakthroughs that are pushing MIPs towards a diagnostic and potential therapeutic reality.