ASPIRIN TABLETS, BASIC USE, PHARMACOLOGY, MECHANISMS, WORKING, DOSE, CONTRAINDICATIONS, SIDE-EFFECTS

ASPIRIN TABLETS, BASIC USE, PHARMACOLOGY, MECHANISMS, WORKING, DOSE, CONTRAINDICATIONS, SIDE-EFFECTS

ASPIRIN TABLETS,
ASPIRIN TABLETS BASIC USE,
ASPIRIN DRUG PROFILE,
ASPIRIN WORKING AND MECHANISMS,
ASPIRIN INDICATION AND USES,
ASPIRIN INDICATIONS AND USES,
ASPIRIN COMBINATION WITH OTHER DRUGS,
ASPIRIN TABLET DOSES,
ASPIRIN EFFERVESCENT TABLET,
ASPIRIN ADVERSE EFFECTS,
ASPIRIN SIDE EFFECTS,
ASPIRIN CONTRAINDICATION

ASPIRIN TABLETS
It is a class of medication called NSAIDS
Non Steroidal Anti inflammatory Drugs
Non-Selective COX inhibitors Class of drug
Chemically it is acetylsalicylic acid.
It is a medication used to reduce pain, fever, or inflammation
Also work as a blood thinner as it prevent clot formation of blood, Antiplatelet action

ASPIRIN TABLETS BASIC USE
Prescribe for following medical conditions (also available OTC)
Heart attack
Risk of stroke
Pain sensations
Fever
Blood thinner
Reduce inflammation

ASPIRIN DRUG PROFILE
Chemical name: acetylsalicylic acid
Routes of administration:
By mouth, rectal,
Lysine acetylsalicylate may be given intravenously or intramuscularly
Bioavailability: 80–100%
Protein binding: 80–90%
Formula: C9H8O4

ASPIRIN WORKING AND MECHANISM
Reduce PG synthesis
Functions of Prostaglandins
Directly Cause Pain
Enhances Pain Inducing Effects Of Bradykinin
Induces Fever
Mediators of pain
Inflammation and fever

Aspirin is non selective inhibitor of cox enzymes and supress & reduce prostaglandin synthesis.
Thus provide its
Anti-inflammatory action
Antiplatelet
Analgesic activity

ASPIRIN INDICATION AND USES
Mild to moderate pain ( headache, backache, joint pain, toothache, dysmenorrhoea)
Antipyretic in fevers
Anti inflammatory in acute rheumatic fever, rheumatoid arthritis, osteoarthritis
Antiplatelet agent in atherosclerotic diseases, post-operative, myocardial infarction, post stroke patients

ASPIRIN INDICATION AND USES
Aspirin is prescribed in a small dose as a means to lower the risk of heart attack (prevents clotting action of platelets)
It can help prevent a heart attack or clot-related stroke by interfering with how the blood clots.
Thus, Aspirin work as a blood thinner to stop it from clotting

ASPIRIN COMBINATION
The combination of clopidogrel and aspirin may lower the risk for major ischemic events among patients with minor ischemic stroke or high-risk transient ischemic attack compared with aspirin alone
Atorvastatin + Aspirin to lower your risk of heart attack and stroke.

ASPIRIN TABLET DOSES
300-600mg TDS analgesic, antipyretic & anti-inflammatory action As per direction of physician
75-150mg OD myocardial infarction/stroke
Usually therapy starts with lower dose to avoid adverse effects

ASPIRIN EFFERVESCENT TABLET
DISPRIN

ASPIRIN ADVERSE EFFECTS, SIDE EFFECTS
Gastric mucosal damage, peptic ulcer
Hypersensitivity
Salicylism—dizziness, tinnitus, vertigo,
Reversible impairment of hearing and vision
Excitement and mental confusion,
Hyperventilation (start to breathe very fast)
Electrolyte imbalance, Liver injury
Acute salicylate poisoning

Peptic ulcer
Bleeding disorder
Hypersensitivity to NSAIDs
Under 12 children
Liver disease
Pregnancy and lactation
Chickenpox of influenza infection


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