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🩺 Intrahepatic Cholestasis of Pregnancy (IHCP): Explained

✅ What It Is

IHCP is a liver disorder that occurs during pregnancy, typically in the third trimester. It causes bile acids (which help digest fats) to build up in the mother’s blood instead of flowing properly into the intestines.

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⚠️ Key Symptoms
• Intense itching, especially on palms and soles
• No visible rash (though scratching may cause marks)
• Often worse at night
• In some cases: dark urine, pale stools, or jaundice

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🧪 How It’s Diagnosed
• Blood tests showing elevated bile acids.
• Liver function tests (LFTs) may show raised transaminases (ALT, AST)
• Diagnosis is clinical + lab-based

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👶 Why It Matters (Risks to Baby)
• Preterm birth
• Meconium-stained amniotic fluid
• Fetal distress
• In rare cases: stillbirth (especially when bile acids -100 µmol/L)

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🩹 Management
• Ursodeoxycholic acid (UDCA) – to reduce bile acids and relieve itching
• Frequent fetal monitoring (non-stress tests, biophysical profiles)
• Early delivery, typically around 36–37 weeks, depending on bile acid levels and symptoms

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🙋‍♀️ Who’s at Higher Risk?
• History of IHCP in previous pregnancies
• Family history of liver disease
• Multiple pregnancies (e.g., twins)
• Certain ethnic backgrounds (e.g., South Asian, South American, Scandinavian)

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