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Study Further Establishes Smoking-Psoriasis Connection
Bill Schu writing in MD reported on a study in the Polish population, published in Postępy, that clarifies and strengthens the link between smoking and the development of psoriasis.

Smoking releases large amounts of free radicals that stimulate cell signaling pathways active in psoriasis. Nicotine present in cigarettes also stimulates dendritic cells, macrophages and keratinocytes, releasing cytokines including tumor necrosis factor (TNF), Interleukin-6, and others. Smoking can also increase the expression of certain genes that can lead to psoriasis.

Comment: The article also mentioned that depression in people with psoriasis may lead them to habits such as smoking.

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