CPIC guideline for celecoxib, flurbiprofen, ibuprofen, lornoxicam and CYP2C9

This is a summary of the CPIC guideline for non-steroidal anti-inflammatory drugs (NSAIDs) and variation in the gene CYP2C9.

This video will focus on the recommendations for celecoxib, flurbiprofen, ibuprofen and lornoxicam. Videos covering the recommendations for meloxicam, piroxicam and tenoxicam as well as a video about the gene-drug pairs with no recommendation in the guideline can be found at the following links:

Meloxicam -    • CPIC guideline for meloxicam and CYP2C9  
Piroxicam and tenoxicam -    • CPIC guideline for tramadol and CYP2D6  
No recommendations -    • CPIC guideline for non-steroidal anti...  

Guideline and supplemental information - https://cpicpgx.org/guidelines/cpic-g...

Annotated guideline and genotype picker - https://www.pharmgkb.org/guidelineAnn...

PharmGKB celecoxib pathway - https://www.pharmgkb.org/pathway/PA16...

PharmGKB flurbiprofen pathway - https://www.pharmgkb.org/pathway/PA16...

PharmGKB ibuprofen pathway - https://www.pharmgkb.org/pathway/PA16...

PharmGKB lornoxicam pathway - https://www.pharmgkb.org/pathway/PA16...

CYP2C9 Gene Information Tables - https://www.pharmgkb.org/page/cyp2c9R...

PharmVar - https://www.pharmvar.org/