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Americans Carolyn R. Bertozzi and Morten Meldal, and Denmark's K. Barry Sharpless have won this year's Nobel Prize for chemistry for their work in developing "click chemistry and bioorthogonal chemistry," Sweden's Karolinska Institute announced on Wednesday.

The award marks the second Nobel for 81-year-old Sharpless, who won the chemistry Nobel in 2001.

Co-winner Bertozzi hopes the prize will be energizing for the field.

"The interface between chemistry and biology is such a rich interface with great technology development and fundamental science discovery. But it’s now time to reflect on how fortunate I’ve been with them and share the celebrations," she told journalists in an interview on Wednesday.

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