Скачать или смотреть Best medicine for depression and sleep. Depression se bahar kaise aaye. Antidepressant for sleep.

In this video, Dr. Mayank Agrawal (Psychiatrist, Mental Health Expert) discusses the best antidepressant medicines for patients with depression and poor sleep (insomnia).

1. Mirtazapine

Strong sedative effect, especially at low doses (7.5–15 mg).

Improves deep slow-wave sleep and helps patients fall asleep faster.

Best suited for depression + insomnia + poor appetite or weight loss.

Side effects: weight gain, daytime sedation.

Advantage: fewer sexual side effects compared to SSRIs/SNRIs.

2. Trazodone

At low doses (25–100 mg), mainly used as a sleep aid.

At higher doses, it also has antidepressant effects.

Less risk of dependence compared to benzodiazepines.

Best for patients already on SSRIs/SNRIs but still struggling with sleep.

Side effects: morning grogginess, rare priapism.

Advantage: minimal sexual side effects.

3. Agomelatine

Works as a melatonin receptor agonist + 5HT2C antagonist.

Helps reset the circadian rhythm and improve natural sleep cycle.

Best for patients with depression + sleep disturbance + circadian rhythm problems (late sleep, jet lag-like pattern).

Side effects: headache, requires liver function monitoring (LFTs).

Not strongly sedating but improves sleep quality naturally.

4. Amitriptyline

A tricyclic antidepressant (TCA) with strong sedative effect.

Helps in depression + insomnia + chronic pain (neuropathic pain, headache, fibromyalgia).

Side effects: dry mouth, constipation, blurred vision, cardiac risk (caution in elderly & heart patients).

Best when depression is associated with pain + poor sleep.

5. Doxepin (Low Dose: 3–6 mg)

FDA-approved for insomnia treatment.

Improves sleep continuity and reduces night-time awakenings.

At higher doses, it also works as an antidepressant.

Best for elderly patients with depression + primary insomnia.

Side effects at higher doses: anticholinergic effects (dry mouth, constipation).

Summary

Mirtazapine → Depression + insomnia + poor appetite

Trazodone → Add-on for insomnia with SSRIs/SNRIs

Agomelatine → Sleep cycle disturbance + depression

Amitriptyline → Depression + insomnia + chronic pain

Low-dose Doxepin → Elderly + depression + insomnia

Best antidepressant for sleep

Mirtazapine for depression and sleep

Trazodone sleep medicine

Agomelatine for depression insomnia

Amitriptyline for depression and pain

Doxepin sleep medicine FDA approved

Depression medicine for sleep

Insomnia treatment without benzodiazepines

#DepressionTreatment #SleepMedicine #Antidepressants #InsomniaTreatment #MentalHealth #Psychiatry #anxietytreatment
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Dr Mayank Agrawal has done MD Neuropsychiatry from Sir JJ group of hospitals Mumbai. He has been trained in Deaddiction under Ministry of health and family welfare. He worked as a Nodal officer under District mental health program. He is renowned child psychiatrist and counselor. He is famous sexologist also. He has extensive experience in the assessment , diagnosis and treatment of psychiatric disorders across different age group. He has good skills in the use of therapeutic communication technique to establish rapport and deliver care to mentally ill patients.

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Disclaimer-The content on this video is offered only as information and it does not constitute solicitation or provision of Medical advice. The content here should not be used as a substitute for obtaining Medical advice from a licensed health care practitioner authorized to practice in your jurisdiction. You should always consult a qualified health care practitioner regarding any specific medical problem or issue.