Скачать или смотреть Prostaglandins Biochemistry | Synthesis and Functions of Prostaglandins | PG analogues & inhibitors

prostaglandzin synthesis , functions and application live biochemistry by dr.ashish agravatt also explained that are used in labour,glaucoma, hypertnsion,gastric ulcer etc
Analogues and inhibitors of prostaglandins
Timeline for Prostaglandins video :
00:00 Introduction to prostaglandins
00:20 Why prostaglandins also called Eicosanoids
00:56 Important eicosanoids(names)
01:20 synthesis of prostaglandins
02:20 primary prostaglandin PGG2
02:30 how steroid act as anti-inflammatory agents
03:00 lipo- oxygenase pathway for leukotrienes synthesis
05:35 functions of prostaglandins
08:38 Prostaglandin analogues as therapeutic agents
10:07 Prostaglandin inhibitors as therapeutic agents
13:07 Summary/revision of prostaglandins

Questions :
Explain Prostaglandins synthesis and functions.Add a note on clinical application of prostaglandin analoques and inhibitors -10 marks (3+3+4)
Functions of prostaglandins. (4M - Nov 2019)
Metabolic basis of role of aspirin as an anti-platelet agent. (2M) (Aug 2019)
The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derived enzymatically from the fatty acid arachidonic acid.

Prostaglandins are powerful locally acting vasodilators and inhibit the aggregation of blood platelets. Through their role in vasodilation, prostaglandins are also involved in inflammation. They are synthesized in the walls of blood vessels and serve the physiological function of preventing needless clot formation, as well as regulating the contraction of smooth muscle tissue. Conversely, thromboxanes (produced by platelet cells) are vasoconstrictors and facilitate platelet aggregation. Their name comes from their role in clot formation (thrombosis).

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