Скачать или смотреть How Is A Drug's MOA Identified During Preclinical Testing? - Pharmaceutical Insights

How Is A Drug's MOA Identified During Preclinical Testing? Have you ever wondered how scientists determine the way a new drug works before it reaches human trials? In this informative video, we'll explain the process of identifying a drug’s mechanism of action during preclinical testing. We'll start by describing how researchers pinpoint potential targets like proteins, enzymes, or receptors in the body that the drug aims to influence. We'll discuss how existing knowledge and screening thousands of compounds help identify promising interactions. You'll learn how tests in test tubes and cultured cells reveal whether the drug binds to or modifies its target, such as reducing enzyme activity. We’ll also cover how scientists observe the effects of the drug on gene activity, protein levels, and cell behavior after binding occurs. Animal models are used to see how the drug behaves in a whole organism, providing insights into its effects. The role of pharmacodynamic studies will be explained, showing how they connect drug levels in the body to the effects observed. Throughout preclinical research, data from various experiments are combined to form a clear picture of how the drug functions. This process is essential for making informed decisions about advancing to human trials and designing effective studies. Join us for this detailed overview of how the mechanism of action is uncovered during drug development, and subscribe for more insights into medicine and pharmacology.

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