Скачать или смотреть “Cyclic GMP | Cellular & Molecular Pharmacology |

Welcome to Complete Educational Notes! In this comprehensive lecture, we dive deep into Cyclic GMP (cGMP)—a vital secondary messenger in cellular and molecular pharmacology. Designed especially for M.Pharm (Pharmacology) first-semester students, this session covers the mechanisms, clinical relevance, drug targets, and exam-focused insights to help you ace GPAT, university finals, and pharmacology coursework.

🧬 What You’ll Learn:
What is cyclic GMP? Biosynthesis via guanylate cyclase, degradation by cGMP phosphodiesterases.

Signal transduction pathways: Role of cGMP in vasodilation, visual phototransduction, and cellular homeostasis.

Receptor systems: Nitric oxide (NO)-mediated soluble guanylyl cyclase vs. particulate guanylyl cyclase.

Drug classes and therapeutic applications:

PDE‑5 inhibitors (sildenafil, tadalafil) for erectile dysfunction and pulmonary hypertension.

NO donors and their impact on vascular physiology.

Molecular regulation: Feedback mechanisms, cross-talk with cAMP.

Clinical relevance and side effects: Hypotension, headache, drug interactions.

Exam tips: Likely GPAT questions, diagram-based answers, short and long answer formats.

Throughout the video, we use handwritten notes, flowcharts, and illustrations to make complex concepts easy to understand. Watch carefully to see exam-focused breakdowns and visual mappings that help you memorize and apply information effectively.

🎯 Who Should Watch:
First-semester M.Pharm (Pharmacology) students aiming for strong fundamentals.

Pharmacy and pharmacy intern students preparing for pharmacology exams.

Aspirants for GPAT, College-level pharmacology exams, and university finals.

💡 Why this video?

Focused on critical exam topics.

Designed for visual learners with annotated diagrams.

Breaks concepts into digestible snippets while maintaining depth.

Includes real-life clinical relevance and therapeutic application.

👍 If you find this helpful:

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Leave your queries or feedback in comments—I'll be glad to clarify!

Together, let's master cGMP signaling and empower your exam success! 🚀

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