Enzyme Inhibition and It's Types | Enzyme Inhibition | Biochemistry

Enzyme Inhibition - This is the video on various types of enzyme inhibition with suitable examples with NEET PG MCQs and theory questions
00:00 - Introduction
00:39 - Examples of theory questions
01:10 - Enzyme inhibition
01:31 - Types of Enzyme Inhibition and Inhibitors
02:20 - Reversible Enzyme Inhibition
02:45 - Types of Reversible Enzyme Inhibition
03:07 - Competitive Enzyme Inhibition
04:29 - Enzyme Kinetics of Competitive Enzyme Inhibition
05:17 - Examples of Competitive Enzyme Inhibition
05:58 - Drugs act as competitive inhibitors
07:40 - Ethanol is used in methanol poisoning
08:35 - Non Competitive Enzyme Inhibition
09:53 - Enzyme Kinetics of Non Competitive Enzyme Inhibition
10:36 - Examples of non-competitive inhibitors
11:17 - Difference between Competitive Enzyme Inhibition and Non Competitive Enzyme Inhibition
12:20 - Uncompetitive Enzyme Inhibition
13:20 - Enzyme Kinetics of Uncompetitive Enzyme Inhibition
14:01 - Irreversible Enzyme Inhibition
14:40 - Types of Irreversible Enzyme Inhibition
15:12 - Substrate Analogue Irreversible Inhibitor or Affinity Labels
15:54 - Group Specific Irreversible Inhibitor
17:41 - Suicide Inhibition or Mechanism Based inactivation
18:40 - Examples of Suicide Inhibition
19:49 - Clinical Applications of Enzyme Inhibitors
20:54 - NEET PG MCQs

Enzyme Inhibition

Any substance that can diminish the velocity of an enzyme reaction is called inhibitor.
Two general classes of inhibitors are:
1. Reversible inhibitor
2. Irreversible inhibitor.
Different types of reversible enzyme inhibition are:
i. Competitive or substrate analogue inhibition
ii. Non-competitive inhibition
iii. Uncompetitive inhibition
Irreversible inhibitors can be divided into three categories:
substrate analogue inhibitor or affinity labels
Group specific inhibitors
suicide inhibitor or mechanism based inactivation.

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