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Скачать или смотреть Fibromyalgia Definition and Interesting Features

  • Health Link
  • 2019-12-10
  • 59
Fibromyalgia Definition and Interesting Features
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Fibromyalgia is a disorder that causes pain all over the body, sleep problems, fatigue, and often emotional and mental distress. Fibromyalgia amplifies painful sensations by affecting the way your brain processes pain signals, meaning people with fibromyalgia are more sensitive to pain than those without the disorder. According to the Centers for Disease Control and Prevention, fibromyalgia affects around 4 million U.S. adults, or about 2 percent of the adult population.

Many of the estimated four million or more Americans living with the widespread pain and fatigue of fibromyalgia struggle to get a diagnosis and effective treatment. Because lab tests often appear normal in these patients, doctors must rely on patients’ symptoms, results from physical exams and the exclusion of other diseases to come to a fibromyalgia diagnosis. Now, researchers at The Ohio State University Wexner Medical Center finally have biologic evidence of the disease through a new experimental testing method that can quickly and accurately diagnose fibromyalgia, while differentiating it from other chronic pain conditions.

“Being able to see the biological differences in the blood of those with fibromyalgia compared to those with other conditions like lupus, osteoarthritis and rheumatoid arthritis finally gives patients validation of their symptoms,” said Dr. Kevin Hackshaw lead author of the study and assistant professor of rheumatology at Ohio State. “Not only does this help us direct treatment, but also prevents the use of unnecessary medications, like opiates, that don’t alleviate fibromyalgia pain and can lead to addiction.”

The laboratory test was developed in a unique collaboration between rheumatologists and the Ohio State food science and technology department. Researchers found that the same technology used to quickly analyze different components in food, like protein and fat, can also analyze chemicals in the blood. “Each person’s blood is unique, like a fingerprint, and this test can show us the intricate details of that fingerprint,” said Dr. Luis Rodriguez-Saona, co-author of the study and professor of food science and technology at Ohio State. “Now, we can see that certain patterns in those fingerprints indicate fibromyalgia, while different ones signal other conditions.”

Future research will validate the test further and hopefully lead to a widely available blood test that can be used in doctors’ offices so that patients can receive a diagnosis in minutes with just a finger prick. Identifying these biological characteristics may also help experts develop novel therapies to treat fibromyalgia.

Fibromyalgia is a chronic syndrome that causes mental stress and bodily pain. It is associated with widespread pain in the bones and muscles, general fatigue and areas of tenderness. Most patients also experience irritable bowel syndrome, tension headaches, temporomandibular disorders, anxiety and depression.

Such symptoms are subjective since they cannot be measured or determined by any tests. It is often confused with other diseases such as arthritis since its symptoms are subjective, and the causes are not precise. However, doctors think that it most likely involves a variety of factors working together such as genetics and because symptoms usually begin to manifest after surgery, infection, physical trauma or significant psychological stress.

Scientists believe that repeated nerve stimulation leads to patients’ brains to change. This change involves an unusual increase in levels of specific chemicals in the brain that signal pain. Additionally, the brain’s receptors seem to acquire a kind of memory pain that exaggerates pain signals.

There is no cure for the syndrome. However, relaxation, exercise, a variety of medications, acupuncture and behavioral therapy usually help in relieving the symptoms and improving sleep quality. Women are traditionally more likely to develop Fibromyalgia than men.

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