Cholangiohepatitis in Dogs: A Case Study - Yuriko Hishiya '22

Presented by Yuriko Hishiya ‘22 (Major: Biology)
Contributors: Dr. Santos, Dr. Gastrock
Faculty Mentor: Charlotte Russell

Cholangiohepatitis is inflammation of the liver, gallbladder, and bile ducts and can be fatal if left untreated. In dogs, cholangiohepatitis is a rare condition and thus has limited documentation. However, early intervention is critical in preventing cirrhosis and further, permanent organ damage. In this case study, a 10 year old Shih Tzu mix presents for lethargy, lack of appetite, and vomiting. Blood work showed elevations in liver function and disruption in bile ducts. With no imaging conducted, the patient was successfully treated with oral medication (pain medication, antibiotics, cholesterol medication, proton-pump inhibitor, and vitamins/supplementation) and fluid support. Blood levels were monitored weekly and returned to normal levels and patient temperament greatly improved after 8 weeks of treatment. Prognosis of cholangiohepatitis is not well known, although this case had a return to normal levels, persistent globulin presented and an abdominal ultrasound taken after treatment showed distension of the gallbladder. This case study illustrates one example of presentation of cholangiohepatitis and may aid in early diagnosis. Given that treatment was successful, this case attempts to give guidance for patients that present similarly.
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