028: REVERSING Chronic KIDNEY DISEASE (CKD): A KETO BREAKTHROUGH! (with Prof. THOMAS WEIMBS, PhD)
We feature Professor Thomas Weimbs, PhD, a pioneering kidney researcher from the University of California, Santa Barbara (UCSB) and Vice Chair of Graduate Studies at the Department of Molecular, Cellular and Developmental Biology (MCDB).
The ketogenic diet (ketogenic metabolic therapy/KMT) is showing promise in reversing Chronic Kidney Disease (CKD), a condition widely considered irreversible. This approach, backed by clinical trials and research, improves kidney function and reduces kidney size in patients with conditions like Polycystic Kidney Disease (PKD) and type 2 diabetes. The key is a ketone body called Beta-hydroxybutyrate (BHB), which acts as a kidney-protective hormone. As research continues, nutritional ketosis is emerging as a powerful tool to manage and potentially reverse CKD, offering new hope to patients.
*PMIDs of Cited Papers: 31631001, 38095025, 36432618, 35664270, 337935200, 337935200, 40547366, 34468402, 38946781
*Weimbs Lab @ UCSB: https://labs.mcdb.ucsb.edu/weimbs/tho...
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TIMESTAMPS
00:00 – Podcast Intro
00:57 – Presenting Dr. Thomas Weimbs
04:04 – What is PKD?
05:47 – Current Challenges in PKD
09:05 – PKD Research Beginnings
15:46 – Role of Glucose
19:25 – Role of BHB
22:46 – Clinical Studies
28:16 – Keto in CKD from T2DM
36:08 – Molecular Mechanisms of Ketones/BHB
41:25 – Role of Exogenous Ketones
49:09 – Nutritional Ketosis vs Exogenous Ketones
52:36 – Plant- vs Meat-Dominant Keto Diets
55:33 – Debunking the Protein Myth vs Kidney
1:01:33 – Pushback from Nephrologists
1:04:16 – Misconceptions & Challenges
1:10:31 – Current Research Frontiers
1:12:24 – How to Reach Prof. Weimbs
1:16:37 – ENDSCREEN Links
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REFERENCES:
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*WHO Top Cause of Death 2019: 👉 https://who.int/news-room/fact-sheets...
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Check out these VIDEOS:
*My own PERSONAL TESTIMONY from a medical professional's perspective in REVERSING MY METABOLIC SYNDROME in the LINKS below!
PART 1 👉 • 001A: I Lost 20 Lbs in 2 Months! (Reversed...
PART 2 👉 • 001B: I Lost 20 Lbs in 2 Months! (Reversed...
*The SCIENCE of the KETOGENIC DIET (Debunking Keto Myths)
👉 • 002: The Science of the KETOGENIC DIET (De...
*INTRO to the LOW CARB HEALTH DOCTOR | LCHD Channel
👉 • 000: The Low Carb Health Doctor | LCHD Glo...
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