Multiple Sclerosis Pathology

We can see multiple sclerosis lesions on MRI scans, but what are they? What is inside of them? This video explains the histopathology of MS from biopsy and autopsy studies and discusses possible treatment implications based on the types of inflammatory cells which are present.

Selected Sources:

Pathology of multiple sclerosis: where do we stand? https://pubmed.ncbi.nlm.nih.gov/23917... Sclerosis: https://www.nejm.org/doi/full/10.1056...
The Pathologic Foundations of Multiple Sclerosis: Current Considerations: https://www.ajmc.com/view/the-patholo...
Pathology of Multiple Sclerosis: https://www.sciencedirect.com/topics/....
Pathological heterogeneity of idiopathic central nervous system inflammatory demyelinating disorders: https://pubmed.ncbi.nlm.nih.gov/18219...
Grey matter pathology in multiple sclerosis: https://www.thelancet.com/journals/la...
Pathology of Multiple Sclerosis: https://www.researchgate.net/publicat...



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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.

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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.