Paving the way to personalized nutrition: insights from ayurveda and metabolomics

Prof. Dr. Kanwal Preet Kochhar
All India Institute of Medical Sciences (AIIMS)
New Delhi | India

Dr. Jyoti Arora
All India Institute of Ayurveda (AIIA)
New Delhi | India

Part of the webinar
Metabolomics India 2024

Title
Paving the way to personalized nutrition: insights from ayurveda and metabolomics

With lifestyle-related metabolic disorders on the rise, effective personalized nutrition approaches are essential. Ayurveda offers a structured framework through the tridosha and prakriti system, classifying individuals into metabolic types — vata, pitta, and kapha — each with distinct physiological and metabolic profiles. Emerging research links prakriti types to specific nuclear receptors that regulate gene expression, impacting metabolic pathways, homeostasis, and phenotype. Studies associate prakriti with gene polymorphisms, inflammation markers, and oxidative stress pathways, suggesting a direct connection between an individual’s genetic profile and metabolic functions. This Ayurveda-based view aligns with metabolomics findings, providing a foundation for targeted health interventions. Additionally, Ayurvedic principles of Rasa (taste-based) therapies highlight variations in taste receptor interactions, affecting nutrient metabolism and bioavailability. By exploring these molecular interactions, we can better understand how diet influences genetic and metabolic pathways, aligning with personalized nutrikinetics. Combining Ayurveda with metabolomics insights promises a holistic approach to precision nutrition. This fusion supports developing tailored dietary interventions to enhance health outcomes, particularly in metabolic and lifestyle diseases.

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