Ep 264- Why the “52 Set Study” Doesn’t Matter

Evidence based practice has unfortunately become a meme, and its meaning, role and utility are less understood than they were just a handful of years ago. In this episode we dive deep, discussing how to incorporate study findings into practice. If you don’t have the ability to gauge the impact of a study’s findings, how do you stay up to date? We answer critical questions like: How does the hierarchy of evidence operate in a field where many meta-analyses have errors? What is the role of mechanistic research compared to applied research, and when should you look to each to inform what you do in the trenches? At a time when many seem ready to simply throw in the towel on the evidence - despite it actually being of a higher quality, than it ever has been, we are here. We are going to bring you back from the brink, so you can make those sweet, sweet evidence based gains.

00:00 Revealing some of the mystery of the cult
https://massresearchreview.com/
Iron Culture Ep. 263- Is Protein Timing Debunked?    • Ep. 263- Is Protein Timing Debunked?  
08:41 Getting into it before the 10 minute mark
12:23 Actually kicking it off… The hierarchy of evidence and meta-analyses
Kadlec 2023 With Great Power Comes Great Responsibility: Common Errors in Meta-Analyses and Meta-Regressions in Strength & Conditioning Research https://pubmed.ncbi.nlm.nih.gov/36208...
32:44 So what actually is a meta-analysis? And which ones to read
42:57 Changes in paradigms
Schoenfeld 2017 Strength and Hypertrophy Adaptations Between Low- vs. High-Load Resistance Training: A Systematic Review and Meta-analysis https://pubmed.ncbi.nlm.nih.gov/28834...
Baz-Valle 2022 A Systematic Review of The Effects of Different Resistance Training Volumes on Muscle Hypertrophy https://pubmed.ncbi.nlm.nih.gov/35291...
Enes 2024 Effects of Different Weekly Set Progressions on Muscular Adaptations in Trained Males: Is There a Dose-Response Effect? https://pubmed.ncbi.nlm.nih.gov/37796...
Damas 2016 Resistance training-induced changes in integrated myofibrillar protein synthesis are related to hypertrophy only after attenuation of muscle damage https://pubmed.ncbi.nlm.nih.gov/27219...
Robinson 2023 Exploring the Dose-Response Relationship Between Estimated Resistance Training Proximity to Failure, Strength Gain, and Muscle Hypertrophy: A Series of Meta-Regressions https://sportrxiv.org/index.php/serve...
57:17 Sources of information and the carrot of capitalism
1:09:19 The research chain and when it should be broken
1:26:26 What we do when we don’t get the study that we want
Smith 2003 Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials https://pubmed.ncbi.nlm.nih.gov/14684...
1:41:32 The final thoughts and a teaser for next time