Don’t Waste Money on Ketosteril! Instead Eat some Fish and Eggs!

Don’t waste Money on Ketosteril !
Instead Eat some Fish and Eggs!!
Gurdon Kay mareez Ketosteril nahin balkay anday aur fish khaain!!

Role of Restricted protein supplemented by KA diet
Ketoacid analogues and essential amino acids and Very low protein diet in CKD

2 types of proteins. Animal proteins and plant based. Protein with high biological value has all 9 essential amino acids not produced in body , egg milk and rice has more BV than meat and fish. Plant protein is like legumes and lentils have less. But if you combine 2 plant based proteins you can have high biological value protein even if you are vegetarian.
More protein leads to more nitrogenous products , inc K and phosphate, acidosis , BUN and creatinine, uremia and hence fall in GFR so if you use very low protein or no protein ... def of essential AA and these KA has nitrogen replaced where they can act as AA but does not produce nitrogen so theoretically all of the side effects should not happen and GFR should be preserved.
Side effects of low or no protein.
Def of essential Amino acids.
PEW and malnutrition
More infections , loss of muscle mass.
But
MDRD did not show benefit , 1990s but did not show benefit
Mostly metamalysis no RCT. Garbage
Supported by drug companies
KDOQi and KDIGO does not support this. Infact of diabetes you should not decrease protein intake to less than 0.8 g /kg
FDA in USA does not approve this
Dose 4-8 tablets TDS. 29000/ month
Vitamins bd supplement industry worth 2019 was 128 billion dollars. US alone 35billions. This is a supplement at its best with NO proven benefit. It is like HCQ for COVID or Sana Maki of COVID not like aspirin in heart disease
if it would have been saving kidneys don’t you think CKD cases or ESKD patients would be decreasing but they are NOT
Why Drs prescribe it.
✔️Patient demand to give a pull for kidneys. It is like asking for pull NOT to age or die !!
✔️Industry pressure and incentives
✔️No time to explain and patients not willing to understand
✔️No therapy available for CKD
100 g meat has more essential Amino acids that 24 tablets
Take Home.
Listen to your doctor.
If GFR less than 45 or Proteinuria more than 0.5 g... Use Low 0.6-0.8 g per kg body weight protein. Use HBV protein so that you get all essential AA. Get enough calories. 30-35 KCL per kg. If your weight is 80 kg so you will take 48 grams per day. In one day you can take
One Egg with 8 grams.
One milk / yogurt -10 gram
30 grams left. 1 piece of chicken , beef or fish.
Bottom line is unless more data available , Don’t take them or take under the supervision of a nephrologist.