Sasha Gusev | Tutorial | Understanding GWAS mechanisms with Transcriptome-Wide Assoc...| CGSI 2022

Sasha Gusev | Understanding GWAS mechanisms with Transcriptome-Wide Association Studies

Related papers:

1. Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation. https://www.biorxiv.org/content/10.11...

2. Yao, D. W., O'Connor, L. J., Price, A. L., & Gusev, A. (2020). Quantifying genetic effects on disease mediated by assayed gene expression levels. Nature genetics, 52(6), 626–633. https://doi.org/10.1038/s41588-020-06...

3. Gusev, A., Lawrenson, K., Lin, X., Lyra, P. C., Jr, Kar, S., Vavra, K. C., Segato, F., Fonseca, M., Lee, J. M., Pejovic, T., Liu, G., Ovarian Cancer Association Consortium, Karlan, B. Y., Freedman, M. L., Noushmehr, H., Monteiro, A. N., Pharoah, P., Pasaniuc, B., & Gayther, S. A. (2019). A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants. Nature genetics, 51(5), 815–823. https://doi.org/10.1038/s41588-019-03...